Functions
1. Enhances endogenous bile acid secretion while reducing reabsorption;
2. Counteracts the cytotoxic effects of hydrophobic bile acids and protects hepatocyte membranes;
3. Aids in dissolving cholesterol stones;
4. Exhibits immunomodulatory properties.
Advantages
1. Product inspection and testing??possesses CMA and CNAS certification.
2. Operates its own R&D center ensuring product quality assurance.
3. As a manufacturer offers competitive pricing.
4. Holds US-FDA approval along with HALAL and Kosher certifications.
5. Ensures prompt delivery coupled with superior after-sales service.
TUDCA vs UDCA
TUDCA (Taurodeoxycholic acid) and UDCA (ursodeoxycholic acid) are both bile acid derivatives utilized in medical practice to address various conditions associated with bile secretion and flow. Notably, there are several key distinctions between them:
1. Chemical Structure: TUDCA is formed by the conjugation of UDCA with taurine, which enhances its water solubility, facilitating intestinal absorption.
2. Mechanism of Action: UDCA primarily functions to dissolve cholesterol gallstones and treat primary biliary cirrhosis (PBC). It effectively substitutes toxic endogenous bile acids, thereby mitigating liver damage. Conversely, TUDCA also offers hepatoprotective effects and exhibits a more pronounced protective influence on specific cell types; it is currently under investigation as a potential therapeutic agent for neurodegenerative disorders.
3. Clinical Applications: While both compounds can be employed in managing certain hepatic diseases, their specific indications may vary significantly. For instance, UDCA is predominantly indicated for PBC treatment, whereas TUDCA has demonstrated efficacy in some studies concerning other liver pathologies such as non-alcoholic steatohepatitis.
4. Side Effects: Both agents are generally well tolerated but may induce mild gastrointestinal disturbances such as diarrhea; however, the incidence and severity of side effects should be evaluated on an individual basis.
When determining which medication to prescribe, it is imperative to adhere to professional medical advice that considers the patient’s unique health circumstances and requirements. If you or your family members are contemplating these treatment options, consulting a healthcare professional for precise information and guidance is essential.
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